Department of Public Health Sciences

Diesel exposure and mortality among railway workers: results of a pilot study

Schenker, M. B., T. Smith, A. Munoz, S. Woskie and F. E. Speizer

Br J Ind Med. 1984. 41(3):320-327.

A pilot study of the mortality of railway workers was undertaken to evaluate the feasibility of studying the association of exposure to diesel exhaust and cause specific mortality. The cohort consisted of 2519 white male subjects aged 45-64 with at least 10 years of railway service by 1967. Subjects were selected on the basis of job classification, and cause specific mortality was ascertained for subjects who died (n = 501) up to 1979. The total follow up period was 28.4 (X 1000) person-years. The standardised mortality ratio (SMR) for the cohort, based on United States national rates, was 87 (95% confidence limits 80, 95), and there were no significant differences from expected number of deaths for any specific neoplasm. The directly standardised rate ratio for respiratory cancer among diesel exposed subjects relative to unexposed subjects was 1.42 +/- 0.50 (means +/- SE). A proportional hazards model was consistent with the findings of the standardised rate ratio, but in neither analysis was the increased risk of respiratory cancer in diesel exposed subjects statistically significant.

Keywords: Age Factors, Air Pollutants, Occupational/*adverse effects, Human, Male, Middle Age, Mortality, Occupational Diseases/*chemically induced, Pilot Projects, *Railroads, Respiratory Tract Neoplasms/*chemically induced/mortality, Retrospective Studies, Support, U.S. Gov't, Non-P.H.S., Support, U.S. Gov't, P.H.S., United States



Close Window

UC Davis Health System is pleased to provide this information for general reference purposes only. It should not be considered as a substitute for professional medical advice. You are urged to consult with your health care provider for diagnosis of and treatment for any health-related condition. The information provided herein may not and should not be used for diagnosis and treatment.

Reproduction of material on this web site is hereby granted solely for personal use. No other use of this material is authorized without prior written approval of UC Regents.