Department of Public Health Sciences

Vitamin A deficiency in non-vitamin-supplemented patients with AIDS: a cross-sectional study

Karter, D. L., A. J. Karter, R. Yarrish, C. Patterson, P. H. Kass, J. Nord and J. W. Kislak

J Acquir Immune Defic Syndr Hum Retrovirol. 1995. 8(2):199-203.

The prevalence of vitamin A deficiency and its association with dietary retinol intake in patients with AIDS was assessed in a cross-sectional study. Sixty eligible patients with AIDS provided serum samples that were analyzed for retinol content. Exclusion criteria included current use of vitamin supplements (57% of the 140 willing to participate) and pregnancy (none). Past dietary intake was determined using a standardized food intake frequency questionnaire. The prevalence of hyporetinemia was 22%. This was a 241-fold greater prevalence than that of a representative sample of the U.S. population, after adjusting for age and sex. There was a positive association between serum retinol status and dietary intake, but 27% of those with adequate intake had serum retinol levels below the normal range. These findings suggest that regardless of intake, patients with AIDS may represent a population at considerable risk of vitamin A deficiency.

Keywords: Acquired Immunodeficiency Syndrome/*complications, Adult, Comparative Study, Cross-Sectional Studies, Diet, Eating, Female, Human, Male, Middle Age, New York City, Nutritional Status, Prevalence, Support, Non-U.S. Gov't, Vitamin A/blood, Vitamin A Deficiency/*complications



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