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Study of Agricultural Lung Disease (SALUD)
This is a cross-sectional study of respiratory function
and paraquat exposure among agricultural workers in Costa Rica. The study
includes two components: (1) an exposure assessment component, and (2)
an epidemiological study with interviewer administered questionnaires
and pulmonary function testing, including single breath diffusion capacity
and oxygen desaturation testing. The specific aims of the study are to:
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Administer a questionnaire on work history, demographics
and health outcomes to at least 450 current farm workers.
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Measure pulmonary function including diffusion capacity
among farm workers in the sample.
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Measure oxygen desaturation using exercise oximetry
in the sample of farm workers.
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Measure current paraquat exposure by biological markers
in a subset of current farm workers.
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Characterize current and cumulative paraquat exposure
among farm workers, based on work histories and exposure assessment
results.
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Evaluate possible independent association of cumulative
long-term paraquat exposure with respiratory symptoms and pulmonary
function in study subjects.
Research
Design and Methods
Investigators
and Staff Contact Information
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